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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
Cea Biomarker, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of <t>CEA</t> <t>and</t> <t>CA199</t> in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).
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CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of CEA and CA199 in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).

Journal: Scientific Reports

Article Title: CD55 may be a new target for colorectal cancer treatment

doi: 10.1038/s41598-025-08491-4

Figure Lengend Snippet: CD55 has diagnostic value for colorectal cancer metastasis. The relationship between clinical test results and tumor metastasis in patients with colorectal cancer was retrospectively analyzed. Data of 1008 patients in Chifeng Municipal Hospital were collected. According to the pathological type, the patients were divided into: simple colorectal cancer group (409 cases), simple liver metastasis group (249 cases), simple lung metastasis group (151 cases), and multiple organ metastasis group (199 cases). (A) Expression of CEA and CA199 in different groups. (B) Expression of CA125 and CA153 in different groups. (C) Changes in white blood cell count, neutrophil ratio, lymphocyte ratio and monocyte ratio. (E) Determination of D-dimer and fibrinogen content. (E, F) The ROC curve method was used to observe the diagnostic efficacy of CEA and CA199 as diagnostic markers in different groups. (G) Peripheral blood samples of 89 subjects were collected and divided into health group ( n = 14), colorectal cancer alone group ( n = 24), liver metastasis only group ( n = 23), lung metastasis only group ( n = 13), and multiple organ metastasis group ( n = 15). The Elias method was used to detect the content of CD55 in peripheral blood. (H, I) The ROC curve method was used to observe the diagnostic efficacy of CD55 as a diagnostic marker among different groups. One-way ANOVA was used when there were more than two groups. The differences were considered significant when the P value was < 0.05. International units of tumor markers: CEA (ng/ml); CA15-3; (U/mL); CA125 (U/mL); CA199 (kU/L). Abbreviation: WBC (White Blood Cell, unit: 109/L); FIB (fibrinogen, unit: g/L); N% (neutrophil ratio); L% (lymphocyte ratio); M% (monocyte ratio).

Article Snippet: Clinical data of CEA, CA199, CA125, CA153, D-D dimer, total WBC count, neutrophil ratio, lymphocyte ratio, monocyte ratio, and Fibrinogen were collected from patients with colorectal cancer in Chifeng Municipal Hospital ( n = 1008).

Techniques: Diagnostic Assay, Expressing, Cell Counting, Marker